| Uniprot ID: | |
| Secondary ID: | |
| Symbol: | miR-122 |
| Other Name: | |
| Class: | Epigenetics |
| Type: | anti-fibrotic |
| Molecular Function: |
| Category I | Category II | Category III |
|---|---|---|
| Intracellular | Epigenetics | microRNA |
Reference Record 1
| PubMed ID | 28544786 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | HSC proliferation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 2
| PubMed ID | 25909171 | Compound ID | |
| CAS | Name | ||
| Model | vitro,human,mice | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting TGF-β-miR-122-FN1/SRF signaling | ||
Reference Record 3
| PubMed ID | 25040043 | Compound ID | |
| CAS | Name | ||
| Model | mice | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | |||
| Process III | |||
| Mechanism | Targeting HIF-1α, vimentin and MAP3K3 | ||
Reference Record 4
| PubMed ID | 23178710 | Compound ID | |
| CAS | Name | ||
| Model | vitro,rat | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | HSCs activation,HSCs proliferation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting P4HA1 | ||
Reference Record 5
| PubMed ID | 22820290 | Compound ID | |
| CAS | Name | ||
| Model | human | Fibrosis Disease | Liver fibrosis |
| Process I | attenue inflammation | ||
| Process II | EMT | ||
| Process III | |||
| Mechanism | |||