| Uniprot ID: | |
| Secondary ID: | |
| Symbol: | miR-145 |
| Other Name: | |
| Class: | Epigenetics |
| Type: | pro/anti-fibrotic |
| Molecular Function: |
| Category I | Category II | Category III |
|---|---|---|
| Intracellular | Epigenetics | microRNA |
Reference Record 1
| PubMed ID | 28091538 | Compound ID | |
| CAS | Name | ||
| Model | vitro,human | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | HSC activation | ||
| Process III | |||
| Mechanism | Targeting krüppel-like factor 4 | ||
Reference Record 2
| PubMed ID | 27922673 | Compound ID | |
| CAS | Name | ||
| Model | vitro,human | Fibrosis Disease | Chondrocyte fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting TNFRSF11B | ||
Reference Record 3
| PubMed ID | 26165705 | Compound ID | |
| CAS | Name | ||
| Model | vitro,human | Fibrosis Disease | Corneal fibrosis |
| Process I | |||
| Process II | fibroblasts differetiation,fibroblasts migration | ||
| Process III | |||
| Mechanism | |||
Reference Record 4
| PubMed ID | 27289031 | Compound ID | |
| CAS | Name | ||
| Model | Fibrosis Disease | Liver fibrosis | |
| Process I | |||
| Process II | |||
| Process III | |||
| Mechanism | |||
Reference Record 5
| PubMed ID | 25876136 | Compound ID | |
| CAS | Name | ||
| Model | vitro,human | Fibrosis Disease | Scar |
| Process I | |||
| Process II | myofibroblasts migration | ||
| Process III | |||
| Mechanism | |||
Reference Record 6
| PubMed ID | 25323858 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 7
| PubMed ID | 23632450 | Compound ID | |
| CAS | Name | ||
| Model | human | Fibrosis Disease | Cystic fibrosis |
| Process I | |||
| Process II | |||
| Process III | |||
| Mechanism | |||
Reference Record 8
| PubMed ID | 23457217 | Compound ID | |
| CAS | Name | ||
| Model | vitro,human,mice | Fibrosis Disease | Pulmonary fibrosis |
| Process I | |||
| Process II | myofibroblasts differentiation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 9
| PubMed ID | 22307526 | Compound ID | |
| CAS | Name | ||
| Model | vitro,human | Fibrosis Disease | Systemic sclerosis |
| Process I | |||
| Process II | |||
| Process III | |||
| Mechanism | |||
Reference Record 10
| PubMed ID | 28902846 | Compound ID | |
| CAS | Name | ||
| Model | vitro,human | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | |||
| Process III | |||
| Mechanism | Targeting ADD3 | ||