| Uniprot ID: | |
| Secondary ID: | |
| Symbol: | miR-146a |
| Other Name: | |
| Class: | Epigenetics |
| Type: | anti-fibrotic |
| Molecular Function: |
| Category I | Category II | Category III |
|---|---|---|
| Intracellular | Epigenetics | microRNA |
Reference Record 1
| PubMed ID | 28739486 | Compound ID | |
| CAS | Name | ||
| Model | vitro,rat | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | HSCs activation,HSCs proliferation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting TGFβ/Smad and LPS/NF-κB/Bambi signaling pathway | ||
Reference Record 2
| PubMed ID | 28510617 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Skeletal muscle fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting TGF-β signaling | ||
Reference Record 3
| PubMed ID | 26647423 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Renal fibrosis |
| Process I | attenue inflammation | ||
| Process II | |||
| Process III | |||
| Mechanism | |||
Reference Record 4
| PubMed ID | 26537990 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | HSCs activation,HSCs proliferation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting Wnt signaling | ||
Reference Record 5
| PubMed ID | 22735812 | Compound ID | |
| CAS | Name | ||
| Model | vitro,rat | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | HSCs proliferation,cells apoptosis | ||
| Process III | |||
| Mechanism | |||