Uniprot ID: | |
Secondary ID: | |
Symbol: | miR-155 |
Other Name: | |
Class: | Epigenetics |
Type: | pro/anti-fibrotic |
Molecular Function: |
Category I | Category II | Category III |
---|---|---|
Intracellular | Epigenetics | microRNA |
Reference Record 1
PubMed ID | 28607031 | Compound ID | |
CAS | Name | ||
Model | vitro | Fibrosis Disease | Cardiac fibrosis |
Process I | |||
Process II | EndoMT | ||
Process III | |||
Mechanism | Targeting TGF-β/miR-155/c-Ski signaling |
Reference Record 2
PubMed ID | 27924974 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Cardiac fibrosis |
Process I | |||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting TGF-β1-Smad 2 signaling |
Reference Record 3
PubMed ID | 27746237 | Compound ID | |
CAS | Name | ||
Model | vitro,human,mice | Fibrosis Disease | Idiopathic pulmonary fibrosis |
Process I | |||
Process II | fibroblasts proliferation | ||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting LXR pathway |
Reference Record 4
PubMed ID | 27284727 | Compound ID | |
CAS | Name | ||
Model | vitro | Fibrosis Disease | Cystic fibrosis |
Process I | |||
Process II | |||
Process III | |||
Mechanism | Targeting CTGF |
Reference Record 5
PubMed ID | 26828700 | Compound ID | |
CAS | Name | ||
Model | vitro,human,mice | Fibrosis Disease | Dermal fibrosis |
Process I | |||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting casein kinase 1α (CK1α) and SHIP-1 |
Reference Record 6
PubMed ID | 25097177 | Compound ID | |
CAS | Name | ||
Model | vitro,human | Fibrosis Disease | Bone marrow fibrosis |
Process I | |||
Process II | |||
Process III | |||
Mechanism |
Reference Record 7
PubMed ID | 24657879 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Cardiac fibrosis |
Process I | |||
Process II | |||
Process III | prevenet collagen deposition | ||
Mechanism |
Reference Record 8
PubMed ID | 19701459 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Pulmonary fibrosis |
Process I | |||
Process II | |||
Process III | |||
Mechanism | Targeting KGF/FGF7 |