Uniprot ID: | |
Secondary ID: | |
Symbol: | miR-370 |
Other Name: | |
Class: | Epigenetics |
Type: | anti-fibrotic |
Molecular Function: |
Category I | Category II | Category III |
---|---|---|
Intracellular | Epigenetics | microRNA |
Reference Record 1
PubMed ID | 28350072 | Compound ID | |
CAS | Name | ||
Model | vitro,rat | Fibrosis Disease | Cardiac fibrosis |
Process I | |||
Process II | fibroblasts-to-myofibroblasts | ||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting TGFβ1-TGFβRI/II-SMAD signaling |
Reference Record 2
PubMed ID | 25686745 | Compound ID | |
CAS | Name | ||
Model | vitro,rat | Fibrosis Disease | Liver fibrosis |
Process I | |||
Process II | HSCs activation,HSCs proliferation,HSCs apoptosis | ||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting Smoothened |