| Uniprot ID: | Q86WI3 |
| Secondary ID: | B5MEF1 |
| Symbol: | NLRC5 |
| Other Name: | NOD27,Caterpiller protein 16.1,CLR16.1,Nucleotide-binding oligomerization domain protein 27,Nucleotide-binding oligomerization domain protein 4 |
| Class: | Single Protein |
| Type: | pro/anti-fibrotic |
| Molecular Function: | Immunity,Innate immunity |
| Category I | Category II | Category III |
|---|---|---|
| Intracellular | Other |
Reference Record 1
| PubMed ID | 28713900 | Compound ID | |
| CAS | Name | ||
| Model | Fibrosis Disease | Cardiac fibrosis | |
| Process I | |||
| Process II | fibroblasts proliferation,fibroblasts migration | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting TGF‑β1/Smad3 signaling pathway | ||
Reference Record 2
| PubMed ID | 28499247 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Cardiac fibrosis |
| Process I | attenue inflammation,regulate cytokines and growth factors | ||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting TLR4/NF-κB. | ||
Reference Record 3
| PubMed ID | 27525969 | Compound ID | |
| CAS | Name | ||
| Model | vitro,human | Fibrosis Disease | Keloid |
| Process I | |||
| Process II | fibroblasts proliferation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting TGF-β signaling | ||