Rapamycin-insensitive companion of mTOR

Basic Information


Uniprot ID: Q6R327
Secondary ID: B2RNX0
Symbol: RICTOR
Other Name: KIAA1999,AVO3 homolog,hAVO3
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Developmental protein


Target Classification


Category I Category II Category III
Intracellular Other

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 28585302 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I attenue inflammation,macrophage migration,regulate cytokines and growth factors
Process II
Process III prevenet collagen deposition
Mechanism Targeting Rictor/mTORC2 signaling

Reference Record 2

PubMed ID 25970154 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I
Process II fibroblasts activation
Process III prevenet collagen deposition
Mechanism Targeting Rictor/mTORC2 signaling