Uniprot ID: | Q14978 |
Secondary ID: | Q15030, Q5VV70, Q9BUV3 |
Symbol: | NOLC1 |
Other Name: | KIAA0035,140 kDa nucleolar phosphoprotein,Nopp140,Hepatitis C virus NS5A-transactivated protein 13,HCV NS5A-transactivated protein 13,Nucleolar 130 kDa protein,Nucleolar phosphoprotein p130 |
Class: | Single Protein |
Type: | pro-fibrotic |
Molecular Function: | ATP-binding,GTP-binding,Nucleotide-binding |
Category I | Category II | Category III |
---|---|---|
Intracellular | Other |
Reference Record 1
PubMed ID | 28133777 | Compound ID | |
CAS | Name | ||
Model | vitro,mice | Fibrosis Disease | Liver fibrosis |
Process I | |||
Process II | HSC activation,HSC proliferation,HSC apoptosis | ||
Process III | prevenet collagen deposition | ||
Mechanism | Targeting TGF-β1 and NF-kB |