Nucleolar and coiled-body phosphoprotein 1

Basic Information


Uniprot ID: Q14978
Secondary ID: Q15030, Q5VV70, Q9BUV3
Symbol: NOLC1
Other Name: KIAA0035,140 kDa nucleolar phosphoprotein,Nopp140,Hepatitis C virus NS5A-transactivated protein 13,HCV NS5A-transactivated protein 13,Nucleolar 130 kDa protein,Nucleolar phosphoprotein p130
Class: Single Protein
Type: pro-fibrotic
Molecular Function: ATP-binding,GTP-binding,Nucleotide-binding


Target Classification


Category I Category II Category III
Intracellular Other

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 28133777 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Liver fibrosis
Process I
Process II HSC activation,HSC proliferation,HSC apoptosis
Process III prevenet collagen deposition
Mechanism Targeting TGF-β1 and NF-kB