Cathepsin B

Basic Information


Uniprot ID: P07858
Secondary ID: B3KQR5
Symbol: CTSB
Other Name: CPSB,APP secretase,APPS,Cathepsin B1,Cathepsin B light chain,Cathepsin B heavy chain
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Hydrolase,Protease,Thiol protease


Target Classification


Category I Category II Category III
Both Enzyme

Related Compound


Target ID Name Interaction
D0564 CA-074Me inhibitor

Fibrosis Related Property


Reference Record 1

PubMed ID 27831566 Compound ID
CAS Name
Model vitro,rat Fibrosis Disease Liver fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 25384123 Compound ID D0564
CAS 147859-80-1 Name CA-074Me
Model pig Fibrosis Disease Pulmonary fibrosis
Process I attenue inflammation
Process II cells apoptosis
Process III prevenet collagen deposition
Mechanism Targeting TGF-β1