Lactoylglutathione lyase

Basic Information

Uniprot ID:	Q04760
Secondary ID:	B2R6P7
Symbol:	GLO1
Other Name:	Aldoketomutase,Glyoxalase I,Glx I,Ketone-aldehyde mutase,Methylglyoxalase,S-D-lactoylglutathione methylglyoxal lyase
Class:	Single Protein
Type:	pro-fibrotic
Molecular Function:	Lyase

Target Classification

Category I	Category II	Category III
Both	Enzyme

Related Compound

Target ID	Name	Interaction
D0078	BrBzGSHCp2	inhibitor
D0079	Ethyl pyruvate	inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID	28231326	Compound ID	D0078
CAS	166038-00-2	Name	BrBzGSHCp2
Model	vitro,rat	Fibrosis Disease	Liver fibrosis
Process I	attenue inflammation
Process II
Process III	prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID	28231326	Compound ID	D0079
CAS	617-35-6	Name	Ethyl pyruvate
Model	vitro,rat	Fibrosis Disease	Liver fibrosis
Process I	attenue inflammation
Process II
Process III	prevenet collagen deposition
Mechanism