Rho guanine nucleotide exchange factor 12

Basic Information


Uniprot ID: Q9NZN5
Secondary ID: O15086, Q6P526
Symbol: ARHGEF12
Other Name: KIAA0382,Leukemia-associated RhoGEF
Class: Single Protein
Type: pro-fibrotic
Molecular Function: GTPase activation,Guanine-nucleotide releasing factor


Target Classification


Category I Category II Category III
Both Other

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 23530122 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism