Heat shock protein HSP 90-beta

Basic Information

Uniprot ID:	P08238
Secondary ID:	B2R5P0
Symbol:	HSP90AB1
Other Name:	HSP90B,HSP 90,Heat shock 84 kDa,HSP 84,HSP84
Class:	Single Protein
Type:	pro-fibrotic
Molecular Function:	Chaperone

Target Classification

Category I	Category II	Category III
Both	Other

Related Compound

Target ID	Name	Interaction
D0546	17-AAG	inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID	28239659	Compound ID	D0546
CAS	75747-14-7	Name	17-AAG
Model	vitro,human,mice	Fibrosis Disease	Idiopathic pulmonary fibrosis
Process I
Process II	fibroblasts proliferation,fibroblast to myofibroblast
Process III	prevenet collagen deposition
Mechanism