Pro-neuregulin-1, membrane-bound isoform

Basic Information


Uniprot ID: Q02297
Secondary ID: A5YAK4
Symbol: NRG1
Other Name: GGF,Pro-NRG1,Acetylcholine receptor-inducing activity,ARIA,Breast cancer cell differentiation factor p45,Glial growth factor,Heregulin,HRG,Neu differentiation factor,Sensory and motor neuron-derived factor,Neuregulin-1,Acetylcholine receptor-inducing activitydivspan class="listify2 inner-title" title="Abbreviation of the full name or an acronym."Short name: span,ARIA,Breast cancer cell differentiation factor p45,Glial growth factor,Heregulindivspan class="listify2 inner-title" title="Abbreviation of the full name or an acronym."Short name: span,HRG,Neu differentiation factor,Sensory and motor neuron-derived factor
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Growth factor


Target Classification


Category I Category II Category III
Both Other

Related Compound



Fibrosis Related Property


Reference Record 1

PubMed ID 27882385 Compound ID
CAS Name
Model vitro,human Fibrosis Disease Keloid
Process I
Process II fibroblasts migration
Process III prevenet collagen deposition
Mechanism Targeting ErbB2-mediated signaling