Guanylyl cyclase

Basic Information

Uniprot ID:
Secondary ID:
Symbol:
Other Name:
Class: Protein Famliy
Type: anti-fibrotic
Molecular Function:

Target Classification

Category I Category II Category III
Other

Related Compound

Target ID Name Interaction
D0262 Ataciguat activator
D0466 Cinaciguat activator

Fibrosis Related Property

Reference Record 1

PubMed ID 24907870 Compound ID D0262
CAS 254877-67-3 Name Ataciguat
Model vitro Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 2

PubMed ID 24567525 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Dermal fibrosis
Process I
Process II fibroblasts activation
Process III prevenet collagen deposition
Mechanism Targeting TGFβ signaling

Reference Record 3

PubMed ID 16770325 Compound ID D0466
CAS 329773-35-5 Name Cinaciguat
Model rat Fibrosis Disease Vascular fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 4

PubMed ID 12270869 Compound ID
CAS Name
Model mice Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting AT1A signaling