Protein kinase C

Basic Information

Uniprot ID:
Secondary ID:
Symbol:
Other Name:
Class:	Protein Famliy
Type:	pro-fibrotic
Molecular Function:

Target Classification

Category I	Category II	Category III
Other

Related Compound

Target ID	Name	Interaction
D0328	Phorbol 12-myristate 13-acetate	inhibitor
D0550	SC-3088	antagonist

Fibrosis Related Property

Reference Record 1

PubMed ID	28061416	Compound ID	D0550
CAS	72361-29-6	Name	SC-3088
Model	vitro	Fibrosis Disease	Liver fibrosis
Process I
Process II	HSC activation,HSC proliferation
Process III
Mechanism	Targeting PKC-dependent GSK3β pathway

Reference Record 2

PubMed ID	23006313	Compound ID	D0328
CAS	16561-29-8	Name	Phorbol 12-myristate 13-acetate
Model	vitro,rat	Fibrosis Disease	Cardiac fibrosis
Process I
Process II	cells apoptosis
Process III	prevenet collagen deposition
Mechanism