Poly (ADP-ribose) polymerase

Basic Information

Uniprot ID:
Secondary ID:
Symbol:
Other Name:
Class:	Protein Famliy
Type:	pro-fibrotic
Molecular Function:

Target Classification

Category I	Category II	Category III
Other

Related Compound

Target ID	Name	Interaction
D0333	3-aminobenzamide	inhibitor
D0467	L-2286	inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID	22846599	Compound ID	D0333
CAS	3544-24-9	Name	3-aminobenzamide
Model	vitro,rat	Fibrosis Disease	Cardiac fibrosis
Process I
Process II
Process III	prevenet collagen deposition
Mechanism	Targeting TGF-β/Smad3 pathway

Reference Record 2

PubMed ID	16716347	Compound ID	D0467
CAS	684276-17-3	Name	L-2286
Model	vitro,rat	Fibrosis Disease	Cardiac fibrosis
Process I
Process II
Process III	prevenet collagen deposition
Mechanism	Targeting GSK-3β

Reference Record 3

PubMed ID	18806606	Compound ID	D0467
CAS	684276-17-3	Name	L-2286
Model	rat	Fibrosis Disease	Cardiac fibrosis
Process I
Process II
Process III	prevenet collagen deposition
Mechanism