Details
spike_validated_epi_1
- Epitope_Source: SARS epitope in PDB database
- Antibody:Antibody m396;Antibody F26G19
- Literature:
Prabakaran P, Gan J, Feng Y, et al. Structure of severe acute respiratory syndrome coronavirus receptor-binding domain complexed with neutralizing antibody. J Biol Chem. 2006;281(23):15829‐15836. doi:10.1074/jbc.M600697200|Pak JE, Sharon C, Satkunarajah M, et al. Structural insights into immune recognition of the severe acute respiratory syndrome coronavirus S protein receptor binding domain. J Mol Biol. 2009;388(4):815‐823. doi:10.1016/j.jmb.2009.03.042
- PDBID:2DD8,3BGF
- PDB_Method:X-RAY
- PDB_Resolution:2.30 Å;3.00 Å
- Epitope_Length:23.0
- Epitope_position: 372 ; 375 ; 376 ; 378 ; 403 ; 404 ; 405 ; 408 ; 437 ; 439 ; 440 ; 449 ; 496 ; 498 ; 499 ; 500 ; 501 ; 502 ; 503 ; 504 ; 505 ; 506 ; 508
Antigenic clustering results between representative variants
- AAA(SARS)
- AAB(BatCoV)
- AAC(SARS-CoV-2)
Heatmap based on antigenicity results between representative variants