Details

spike_validated_epi_12

  • Epitope_Source: Sars-Cov-2 epitope in PDB database
  • Antibody:Antibody H014 FAB
  • Literature:
    Lv Z, Deng YQ, Ye Q, Cao L, Sun CY, Fan C, Huang W, Sun S, Sun Y, Zhu L, Chen Q, Wang N, Nie J, Cui Z, Zhu D, Shaw N, Li XF, Li Q, Xie L, Wang Y, Rao Z, Qin CF, Wang X. Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody. Science. 2020 Sep 18;369(6510):1505-1509. doi: 10.1126/science.abc5881. Epub 2020 Jul 23. PMID: 32703908; PMCID: PMC7402622.
  • PDBID:7CAH
  • PDB_Method:EM
  • PDB_Resolution:3.90 Å
  • Epitope_Length:18.0
  • Epitope_position: 369 ; 372 ; 373 ; 374 ; 375 ; 376 ; 377 ; 378 ; 379 ; 380 ; 385 ; 405 ; 407 ; 408 ; 411 ; 412 ; 503 ; 504
Antigenic clustering results between representative variants
  • AAA(SARS)
  • AAB(BatCoV)
  • AAC(SARS-CoV-2)
Heatmap based on antigenicity results between representative variants