Details

spike_validated_epi_14

  • Epitope_Source: Sars-Cov-2 epitope in PDB database
  • Antibody:Antibody 4A8
  • Literature:
    Chi X, Yan R, Zhang J, Zhang G, Zhang Y, Hao M, Zhang Z, Fan P, Dong Y, Yang Y, Chen Z, Guo Y, Zhang J, Li Y, Song X, Chen Y, Xia L, Fu L, Hou L, Xu J, Yu C, Li J, Zhou Q, Chen W. A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2. Science. 2020 Aug 7;369(6504):650-655. doi: 10.1126/science.abc6952. Epub 2020 Jun 22. PMID: 32571838; PMCID: PMC7319273.
  • PDBID:7C2L
  • PDB_Method:EM
  • PDB_Resolution:3.10 Å
  • Epitope_Length:11.0
  • Epitope_position: 144 ; 145 ; 146 ; 147 ; 150 ; 152 ; 245 ; 246 ; 247 ; 248 ; 249
Antigenic clustering results between representative variants
  • AAA(SARS)
  • AAB(BatCoV)
  • AAC(SARS-CoV-2)
Heatmap based on antigenicity results between representative variants