spike_validated_epi_3

• Epitope_Source： Sars-Cov-2 epitope in PDB database
• Antibody：Antibody B38, Antibody cv30 fab, CC12.3, CC12.1, COVA2-04
• Literature：
  Wu Y, Wang F, Shen C, et al. A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2 [published online ahead of print, 2020 May 13]. Science. 2020;eabc2241. doi:10.1126/science.abc2241 Hurlburt NK, Wan YH, Stuart AB, Feng J, McGuire AT, Stamatatos L, Pancera M. Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation. bioRxiv [Preprint]. 2020 Jun 12:2020.06.12.148692. doi: 10.1101/2020.06.12.148692. PMID: 32577631; PMCID: PMC7301900. Yuan M, Liu H, Wu NC, Lee CD, Zhu X, Zhao F, Huang D, Yu W, Hua Y, Tien H, Rogers TF, Landais E, Sok D, Jardine JG, Burton DR, Wilson IA. Structural basis of a shared antibody response to SARS-CoV-2. Science. 2020 Aug 28;369(6507):1119-1123. doi: 10.1126/science.abd2321. Epub 2020 Jul 13. PMID: 32661058; PMCID: PMC7402627. Wu NC, Yuan M, Liu H, Lee CD, Zhu X, Bangaru S, Torres JL, Caniels TG, Brouwer PJM, van Gils MJ, Sanders RW, Ward AB, Wilson IA. An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain. bioRxiv [Preprint]. 2020 Jul 27:2020.07.26.222232. doi: 10.1101/2020.07.26.222232. PMID: 32743580; PMCID: PMC7386498.
• PDBID：7BZ5, 6XE1, 6XC4, 6XC7, 6XC2, 6XC3, 7JMO
• PDB_Method：X-RAY
• PDB_Resolution：1.84 Å, 2.75 Å, 2.34 Å, 2.88 Å, 3.11 Å, 2.70 Å, 2.36 Å
• Epitope_Length：30.0
• Epitope_position： 403 ; 405 ; 409 ; 415 ; 416 ; 417 ; 420 ; 421 ; 453 ; 455 ; 456 ; 457 ; 458 ; 460 ; 473 ; 475 ; 476 ; 477 ; 486 ; 487 ; 489 ; 490 ; 493 ; 495 ; 496 ; 498 ; 500 ; 501 ; 502 ; 505