Details

spike_validated_epi_8

  • Epitope_Source: Sars-Cov-2 epitope in PDB database
  • Antibody:Antibody Fab 2-4
  • Literature:
    Liu L, Wang P, Nair MS, Yu J, Rapp M, Wang Q, Luo Y, Chan JF, Sahi V, Figueroa A, Guo XV, Cerutti G, Bimela J, Gorman J, Zhou T, Chen Z, Yuen KY, Kwong PD, Sodroski JG, Yin MT, Sheng Z, Huang Y, Shapiro L, Ho DD. Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike. Nature. 2020 Aug;584(7821):450-456. doi: 10.1038/s41586-020-2571-7. Epub 2020 Jul 22. PMID: 32698192.
  • PDBID:6XEY
  • PDB_Method:EM
  • PDB_Resolution:3.25 Å
  • Epitope_Length:14.0
  • Epitope_position: 449 ; 453 ; 455 ; 456 ; 483 ; 484 ; 485 ; 486 ; 487 ; 489 ; 490 ; 492 ; 493 ; 494
Antigenic clustering results between representative variants
  • AAA(SARS)
  • AAB(BatCoV)
  • AAC(SARS-CoV-2)
Heatmap based on antigenicity results between representative variants