Disorder "Cancer"
Found 11 records
Disorder information
Disorder name:
Cancer
Disoder ID:
Synonyms:
malignant neoplasm,malignant tumor,primary cancer
Definition:
An organ or organ-system abnormality that consists of uncontrolled autonomous cell-proliferation which can occur in any part of the body as a benign or malignant neoplasm (tumour).
Modifier statisitcs
Record:
11
Gene:
10
Variant:
11
Reference:
4
Effect type:
Expressivity(11)
Modifier effect:
Risk factor(9)
,Altered susceptibility(1)
,Altered severity(1)
| Modifier gene | Variant | Effect type | Modifier effect | Evidence | Effect | PubMed ID |
|---|---|---|---|---|---|---|
| ABCC5 | ABCC5:c.A-1629T | Expressivity | Altered severity | From review article | ABCC5 (A-1629T, rs7627754) was associated with significant reductions in ejection and shortening fractions in survivors homozygousmore | more |