PNU282987

Basic Information

CAS ID: 711085-63-1
Molecular Formula: C14H17ClN2O
Molecular Weight: 264.8 g/mol
Monoisotopic Mass: 264.1029 g/mol
Class: Small Molecule
Natural Product: No
Other Names: PNU-282987
Analysis: Drug repositioning mechanism analysis

Cl O NH N

Compound Structure and Identifier

InChI: InChI=1S/C14H17ClN2O/c15-12-3-1-11(2-4-12)14(18)16-13-9-17-7-5-10(13)6-8-17/h1-4,10,13H,5-9H2,(H,16,18)/t13-/m0/s1 See All
InChI Key: WECKJONDRAUFDD-ZDUSSCGKSA-N
Smiles: Clc1ccc(cc1)C(=O)N[C@H]2CN3CCC2CC3 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0158 Neuronal acetylcholine receptor subunit alpha-7 agonist

Related Fibrosis Property

Reference Record 1

PubMed ID 28732106 Target ID T0158
Uniprot ID Neuronal acetylcholine receptor subunit alpha-7 Name Neuronal acetylcholine receptor subunit alpha-7
Model mice Fibrosis Disease Cardiac fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism Targeting TGF-β1/Smad3 pathway

Related Link

PubChem: 9795278
ChEMBL: CHEMBL177611