Neuronal acetylcholine receptor subunit alpha-7

Basic Information


Uniprot ID: P36544
Secondary ID: A8K7Q4
Symbol: CHRNA7
Other Name: NACHRA7
Class: Single Protein
Type: anti-fibrotic
Molecular Function: Ion channel,Ligand-gated ion channel,Receptor


Target Classification


Category I Category II Category III
Extracellular Ion channel protein Nicotinic acetylcholine receptor

Related Compound


Target ID Name Interaction
D0021 PNU282987 agonist

Fibrosis Related Property


Reference Record 1

PubMed ID 28732106 Compound ID D0021
CAS 711085-63-1 Name PNU282987
Model mice Fibrosis Disease Cardiac fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism Targeting TGF-β1/Smad3 pathway

Reference Record 2

PubMed ID 28283678 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Pulmonary fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism Targeting PTP1B