Alprostadil

Basic Information

CAS ID: 745-65-3
Molecular Formula: C20H34O5
Molecular Weight: 354.5 g/mol
Monoisotopic Mass: 354.2406 g/mol
Class: Small Molecule
Natural Product: No
Other Names: VITAROS | VIRIDAL 5 | PGE1 | PROSTIN VR PEDIATRIC | VIRIDAL DUO | CAVERJECT | PROSTIN | EDEX | PROSTAGLANDIN E1 | VIRIDAL 10 | VIRIDAL 20 | ALPROSTADIL | PROSTIN VR | CAVERJECT IMPULSE | U-10,136
Analysis: Drug repositioning mechanism analysis

OH OH O O HO

Compound Structure and Identifier

InChI: InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1 See All
InChI Key: GMVPRGQOIOIIMI-DWKJAMRDSA-N
Smiles: CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O See All
Molfile: Download

Related Target

Target ID Name Interaction
T0129 Prostaglandin E2 receptor EP1 subtype agonist
T0130 Prostaglandin E2 receptor EP2 subtype agonist

Related Fibrosis Property

Reference Record 1

PubMed ID 28644845 Target ID T0130
Uniprot ID Prostaglandin E2 receptor EP2 subtype Name Prostaglandin E2 receptor EP2 subtype
Model vitro Fibrosis Disease Keloid
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting ERK/Ets-1 signaling

Reference Record 2

PubMed ID 28644845 Target ID T0129
Uniprot ID Prostaglandin E2 receptor EP1 subtype Name Prostaglandin E2 receptor EP1 subtype
Model vitro Fibrosis Disease Keloid
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting ERK/Ets-1 signaling

Related Link

PubChem: 5280723
ChEMBL: CHEMBL495