Amlodipine

Basic Information

CAS ID: 88150-42-9
Molecular Formula: C20H25ClN2O5
Molecular Weight: 408.9 g/mol
Monoisotopic Mass: 408.1452 g/mol
Class: Small Molecule
Natural Product: No
Other Names: UK-48340-11 | UK-48,340-11 | UK-48,340-26 | NORVAS | UK-48340-26 | NORVASC | ISTIN | AMLODIPINE BESYLATE | ASTUDAL 5 | AMLODIPINE | AMLODIPINE BESILATE | AMLODIPINE MALEATE | AMVAZ
Analysis: Drug repositioning mechanism analysis

O O O H2N NH Cl O O

Compound Structure and Identifier

InChI: InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3 See All
InChI Key: HTIQEAQVCYTUBX-UHFFFAOYSA-N
Smiles: CCOC(=O)C1=C(COCCN)NC(=C(C1c2ccccc2Cl)C(=O)OC)C See All
Molfile: Download

Related Target

Target ID Name Interaction
T0907 Sphingomyelin phosphodiesterase inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 19635928 Target ID T0907
Uniprot ID Sphingomyelin phosphodiesterase Name Sphingomyelin phosphodiesterase
Model vitro,human,mice Fibrosis Disease Cystic fibrosis
Process I attenue inflammation
Process II
Process III
Mechanism

Reference Record 2

PubMed ID 28595719 Target ID
Uniprot ID Name
Model rat Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 2162
ChEMBL: CHEMBL1491