AICA ribonucleotide

Basic Information

CAS ID: 3031-94-5
Molecular Formula: C9H15N4O8P
Molecular Weight: 338.2 g/mol
Monoisotopic Mass: 338.0628 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

NH2 O N N O O P O OH HO HO OH NH2

Compound Structure and Identifier

InChI: InChI=1S/C9H15N4O8P/c10-7-4(8(11)16)12-2-13(7)9-6(15)5(14)3(21-9)1-20-22(17,18)19/h2-3,5-6,9,14-15H,1,10H2,(H2,11,16)(H2,17,18,19)/t3-,5-,6-,9-/m1/s1 See All
InChI Key: NOTGFIUVDGNKRI-UUOKFMHZSA-N
Smiles: NC(=O)c1ncn([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)c1N See All
Molfile: Download

Related Target

Target ID Name Interaction
T0381 5'-AMP-activated protein kinase catalytic subunit alpha-1 agonist

Related Fibrosis Property

Reference Record 1

PubMed ID 28593136 Target ID T0381
Uniprot ID 5'-AMP-activated protein kinase catalytic subunit alpha-1 Name 5'-AMP-activated protein kinase catalytic subunit alpha-1
Model vitro Fibrosis Disease Liver fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting TGF-β

Reference Record 2

PubMed ID 25503637 Target ID T1021
Uniprot ID AMP-activated protein kinase Name AMP-activated protein kinase
Model rat Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID 23825068 Target ID
Uniprot ID Name
Model rat Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting AMPK

Reference Record 4

PubMed ID 21567395 Target ID T1021
Uniprot ID AMP-activated protein kinase Name AMP-activated protein kinase
Model vitro Fibrosis Disease Liver fibrosis
Process I
Process II myofibroblasts differentiation
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 65110
ChEMBL: CHEMBL483849