AMP-activated protein kinase

Basic Information

Uniprot ID:
Secondary ID:
Symbol:
Other Name:
Class: Protein Famliy
Type: anti-fibrotic
Molecular Function:

Target Classification

Category I Category II Category III
Other

Related Compound

Target ID Name Interaction
D0080 Metformin agonist

Fibrosis Related Property

Reference Record 1

PubMed ID 25503637 Compound ID D0043
CAS 3031-94-5 Name AICA ribonucleotide
Model rat Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 21567395 Compound ID D0043
CAS 3031-94-5 Name AICA ribonucleotide
Model vitro Fibrosis Disease Liver fibrosis
Process I
Process II myofibroblasts differentiation
Process III prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID 21567395 Compound ID D0080
CAS 657-24-9 Name Metformin
Model vitro Fibrosis Disease Liver fibrosis
Process I
Process II myofibroblasts differentiation
Process III prevenet collagen deposition
Mechanism

Reference Record 4

PubMed ID 18098312 Compound ID
CAS Name
Model vitro Fibrosis Disease Liver fibrosis
Process I
Process II HSCs activation,HSCs proliferation
Process III
Mechanism

Reference Record 5

PubMed ID 28918029 Compound ID
CAS Name
Model rat Fibrosis Disease Cardiac fibrosis
Process I
Process II fibroblasts proliferation
Process III prevenet collagen deposition
Mechanism Targeting p21/p27 and miR-29 family