ARQ-092

Basic Information

CAS ID: 1313881-70-7
Molecular Formula: C27H24N6
Molecular Weight: 432.531 g/mol
Monoisotopic Mass: 432.206 g/mol
Class: Small Molecule
Natural Product: No
Other Names: 2-Pyridinamine, 3-[3-[4-(1-aminocyclobutyl)phenyl]-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl]-|3-[3-[4-(1-Aminocyclobutyl)phenyl]-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl]-2-pyridinamine
Analysis: Drug repositioning mechanism analysis

N N N N NH2 H2N

Compound Structure and Identifier

InChI: InChI=1S/C27H24N6/c28-24-21(8-4-17-30-24)25-32-23-14-13-22(18-6-2-1-3-7-18)31-26(23)33(25)20-11-9-19(10-12-20)27(29)15-5-16-27/h1-4,6-14,17H,5,15-16,29H2,(H2,28,30) See All
InChI Key: HNFMVVHMKGFCMB-UHFFFAOYSA-N
Smiles: C1CC(C1)(C2=CC=C(C=C2)N3C4=C(C=CC(=N4)C5=CC=CC=C5)N=C3C6=C(N=CC=C6)N)N See All
Molfile:

Related Target

Target ID Name Interaction
T0360 RAC-alpha serine/threonine-protein kinase inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 28566435 Target ID T0360
Uniprot ID RAC-alpha serine/threonine-protein kinase Name RAC-alpha serine/threonine-protein kinase
Model vitro,rat Fibrosis Disease Liver fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting AKT phosphorylation

Related Link

PubChem: 53262401
ChEMBL: