| CAS ID: | 128517-07-7 |
| Molecular Formula: | C24H36N4O6S2 |
| Molecular Weight: | 540.7 g/mol |
| Monoisotopic Mass: | 540.2076 g/mol |
| Class: | Small Molecule |
| Natural Product: | No |
| Other Names: | ISTODAX | FK228 | Chromadax | ROMIDEPSIN | FR901228 |
| Analysis: | Drug repositioning mechanism analysis |
| InChI: | InChI=1S/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-12H2,1-5H3,(H,25,31)(H,26,32)(H,27,29)(H,28,30)/b9-7+,16-6-/t15-,17-,19-,20+/m1/s1 | See All |
| InChI Key: | OHRURASPPZQGQM-GCCNXGTGSA-N | |
| Smiles: | C\C=C\1/NC(=O)[C@H]2CSSCC\C=C\[C@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@@H](NC1=O)C(C)C | See All |
| Molfile: | Download |
Reference Record 1
| PubMed ID | 28467787 | Target ID | T0674 |
| Uniprot ID | Histone deacetylase 1 | Name | Histone deacetylase 1 |
| Model | vitro,mice | Fibrosis Disease | Idiopathic pulmonary fibrosis |
| Process I | |||
| Process II | fibroblasts proliferation,fibroblasts-to-myofibroblasts | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting LOX expression | ||
| PubChem: | 5352062 |
| ChEMBL: | CHEMBL343448 |