Histone deacetylase 1

Basic Information

Uniprot ID:	Q13547
Secondary ID:	Q92534
Symbol:	HDAC1
Other Name:	RPD3L1
Class:	Epigenetics
Type:	pro-fibrotic
Molecular Function:	Chromatin regulator,Hydrolase,Repressor

Target Classification

Category I	Category II	Category III
Intracellular	Epigenetics	Eraser

Related Compound

Target ID	Name	Interaction
D0056	Romidepsin	inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID	28467787	Compound ID	D0056
CAS	128517-07-7	Name	Romidepsin
Model	vitro,mice	Fibrosis Disease	Idiopathic pulmonary fibrosis
Process I
Process II	fibroblasts proliferation,fibroblasts-to-myofibroblasts
Process III	prevenet collagen deposition
Mechanism	Targeting LOX expression