| CAS ID: | 32222-06-3 |
| Molecular Formula: | C27H44O3 |
| Molecular Weight: | 416.7 g/mol |
| Monoisotopic Mass: | 416.329 g/mol |
| Class: | Small Molecule |
| Natural Product: | No |
| Other Names: | SILKIS | RO 21-5535 | 14Alpha-H,1Alpha,25-Dihydroxyvitamin D3 | 1ALPHA,25-DIHYDROXYVITAMIN D3 | VECTICAL | Dihydroxycholecalciferol | CALCITRIOL | 1ALPHA,25-DIHYDROXYCHOLECALCIFEROL | Topitriol | ROCALTROL | CALCIJEX | Dihydroxyvitamin D 3 |
| Analysis: | Drug repositioning mechanism analysis |
| InChI: | InChI=1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1 | See All |
| InChI Key: | GMRQFYUYWCNGIN-NKMMMXOESA-N | |
| Smiles: | C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2\C(=C\C=C/3\C[C@@H](O)C[C@H](O)C3=C)\CCC[C@]12C | See All |
| Molfile: | Download |
Reference Record 1
Reference Record 2
| PubMed ID | 28216152 | Target ID | |
| Uniprot ID | Name | ||
| Model | vitro,rat | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 3
| PubMed ID | 26578366 | Target ID | |
| Uniprot ID | Name | ||
| Model | mice | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 4
| PubMed ID | 28901396 | Target ID | |
| Uniprot ID | Name | ||
| Model | vitro,mice | Fibrosis Disease | Peritoneal fibrosis |
| Process I | |||
| Process II | |||
| Process III | |||
| Mechanism | |||