AM6545

Basic Information

CAS ID: 1245626-05-4
Molecular Formula: C26H23Cl2N5O3S
Molecular Weight: 556.5 g/mol
Monoisotopic Mass: 555.0899 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

N N Cl Cl N O NH N S O O

Compound Structure and Identifier

InChI: InChI=1S/C26H23Cl2N5O3S/c1-18-24(26(34)31-32-13-15-37(35,36)16-14-32)30-33(23-11-10-21(27)17-22(23)28)25(18)20-8-6-19(7-9-20)5-3-2-4-12-29/h6-11,17H,2,4,13-16H2,1H3,(H,31,34) See All
InChI Key: XBHQLFVDGLPBCK-UHFFFAOYSA-N
Smiles: Cc1c(nn(c2ccc(Cl)cc2Cl)c1c3ccc(cc3)C#CCCC#N)C(=O)NN4CCS(=O)(=O)CC4 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0134 Cannabinoid receptor 1 antagonist

Related Fibrosis Property

Reference Record 1

PubMed ID 28422760 Target ID T0134
Uniprot ID Cannabinoid receptor 1 Name Cannabinoid receptor 1
Model vitro,human,mice Fibrosis Disease Idiopathic pulmonary fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism Targeting CB1R and iNOS activity

Related Link

PubChem: 46912919
ChEMBL: CHEMBL3341898