Phloretin

Basic Information

CAS ID: 60-82-2
Molecular Formula: C15H14O5
Molecular Weight: 274.3 g/mol
Monoisotopic Mass: 274.0841 g/mol
Class: Small Molecule
Natural Product: Yes
Other Names: Phloretin | 2',4,4',6'-Tetrahydroxydihydrochalcone | 2',4,4',6'-Tetrahydroxy-Dihydrochalcone
Analysis: Drug repositioning mechanism analysis

HO O HO OH OH

Compound Structure and Identifier

InChI: InChI=1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2 See All
InChI Key: VGEREEWJJVICBM-UHFFFAOYSA-N
Smiles: Oc1ccc(CCC(=O)c2c(O)cc(O)cc2O)cc1 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0174 Solute carrier family 2, facilitated glucose transporter member 1 inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 27997810 Target ID T0174
Uniprot ID Solute carrier family 2, facilitated glucose transporter member 1 Name Solute carrier family 2, facilitated glucose transporter member 1
Model vitro,mice Fibrosis Disease Pulmonary fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting GLUT1-dependent glycolysis

Related Link

PubChem: 4788
ChEMBL: CHEMBL45068