Solute carrier family 2, facilitated glucose transporter member 1

Basic Information

Uniprot ID:	P11166
Secondary ID:	A8K9S6
Symbol:	SLC2A1
Other Name:	GLUT1,Glucose transporter type 1, erythrocytebrain,GLUT-1,HepG2 glucose transporter
Class:	Single Protein
Type:	pro-fibrotic
Molecular Function:	Sugar transport,Transport

Target Classification

Category I	Category II	Category III
Extracellular	Transporter	Solute carrier family

Related Compound

Target ID	Name	Interaction
D0097	Phloretin	inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID	27997810	Compound ID	D0097
CAS	60-82-2	Name	Phloretin
Model	vitro,mice	Fibrosis Disease	Pulmonary fibrosis
Process I
Process II
Process III	prevenet collagen deposition
Mechanism	Targeting GLUT1-dependent glycolysis

Reference Record 2

PubMed ID	27480571	Compound ID
CAS		Name
Model	vitro,mice	Fibrosis Disease	Idiopathic pulmonary fibrosis
Process I
Process II	cells proliferation
Process III	prevenet collagen deposition
Mechanism	Targeting TGF-β signaling