GANT61

Basic Information

CAS ID: 500579-04-4
Molecular Formula: C27H35N5
Molecular Weight: 429.6 g/mol
Monoisotopic Mass: 429.2892 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

N N N N N

Compound Structure and Identifier

InChI: InChI=1S/C27H35N5/c1-29(2)25-12-7-5-10-23(25)20-31-18-9-19-32(27(31)22-14-16-28-17-15-22)21-24-11-6-8-13-26(24)30(3)4/h5-8,10-17,27H,9,18-21H2,1-4H3 See All
InChI Key: KVQOGDQTWWCZFX-UHFFFAOYSA-N
Smiles: CN(C)c1ccccc1CN2CCCN(Cc3ccccc3N(C)C)C2c4ccncc4 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0603 Zinc finger protein GLI2 inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 26193634 Target ID T0603
Uniprot ID Zinc finger protein GLI2 Name Zinc finger protein GLI2
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I
Process II cells proliferation
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 27793816 Target ID T0603
Uniprot ID Zinc finger protein GLI2 Name Zinc finger protein GLI2
Model vitro,human,mice Fibrosis Disease Systemic sclerosis
Process I
Process II fibroblasts activation
Process III prevenet collagen deposition
Mechanism Targeting TGF-β signaling

Related Link

PubChem: 421610
ChEMBL: CHEMBL471728