Crenolanib

Basic Information

CAS ID: 670220-88-9
Molecular Formula: C26H29N5O2
Molecular Weight: 443.6 g/mol
Monoisotopic Mass: 443.2321 g/mol
Class: Small Molecule
Natural Product: No
Other Names: CRENOLANIB | CP-868596 | CRENOLANIB BESYLATE | ARO-002 | 596-26 | CP-868 | ARO-002-26
Analysis: Drug repositioning mechanism analysis

O N N N NH2 N O

Compound Structure and Identifier

InChI: InChI=1S/C26H29N5O2/c1-26(14-32-15-26)16-33-20-6-7-22-21(13-20)28-17-31(22)24-8-5-18-3-2-4-23(25(18)29-24)30-11-9-19(27)10-12-30/h2-8,13,17,19H,9-12,14-16,27H2,1H3 See All
InChI Key: DYNHJHQFHQTFTP-UHFFFAOYSA-N
Smiles: CC1(COc2ccc3c(c2)ncn3c4ccc5cccc(N6CCC(N)CC6)c5n4)COC1 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0024 Platelet-derived growth factor receptor alpha inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 27569721 Target ID T0024
Uniprot ID Platelet-derived growth factor receptor alpha Name Platelet-derived growth factor receptor alpha
Model vitro,mice Fibrosis Disease Muscle fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 10366136
ChEMBL: CHEMBL2105728