Forskolin

Basic Information

CAS ID: 66575-29-9
Molecular Formula: C22H34O7
Molecular Weight: 410.5 g/mol
Monoisotopic Mass: 410.2305 g/mol
Class: Small Molecule
Natural Product: Yes
Other Names: Colforsin | FORSKOLIN | HL 362 | BOFORSIN | L 75 1362B
Analysis: Drug repositioning mechanism analysis

O O OH OH OH O O

Compound Structure and Identifier

InChI: InChI=1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1 See All
InChI Key: OHCQJHSOBUTRHG-KGGHGJDLSA-N
Smiles: CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]3(O)C(=O)C[C@@](C)(O[C@]13C)C=C See All
Molfile: Download

Related Target

Target ID Name Interaction
T0572 Zinc finger protein GLI1 inhibitor
T1049 Cyclic adenosine monophosphate activator

Related Fibrosis Property

Reference Record 1

PubMed ID 18050204 Target ID T1049
Uniprot ID Cyclic adenosine monophosphate Name Cyclic adenosine monophosphate
Model vitro,human Fibrosis Disease Fibrosis
Process I
Process II myofibroblasts differentiation
Process III
Mechanism

Reference Record 2

PubMed ID 27590029 Target ID T0572
Uniprot ID Zinc finger protein GLI1 Name Zinc finger protein GLI1
Model rat Fibrosis Disease Liver fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism Targeting Hh signaling

Related Link

PubChem: 47936
ChEMBL: CHEMBL52606