Zinc finger protein GLI1

Basic Information


Uniprot ID: P08151
Secondary ID: D0EUY3
Symbol: GLI1
Other Name: GLI,Glioma-associated oncogene,Oncogene GLI
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Activator,Developmental protein,DNA-binding


Target Classification


Category I Category II Category III
Intracellular Other transcription factor Transcription activator

Related Compound


Target ID Name Interaction
D0108 Forskolin inhibitor

Fibrosis Related Property


Reference Record 1

PubMed ID 28457748 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Bone marrow fibrosis
Process I
Process II myofibroblasts differentiaon
Process III
Mechanism

Reference Record 2

PubMed ID 27590029 Compound ID D0108
CAS 66575-29-9 Name Forskolin
Model rat Fibrosis Disease Liver fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism Targeting Hh signaling