22(S)-Hydroxycholesterol

Basic Information

CAS ID: 22348-64-7
Molecular Formula: C27H46O2
Molecular Weight: 402.7 g/mol
Monoisotopic Mass: 402.3498 g/mol
Class: Small Molecule
Natural Product: No
Other Names: 22(S)-Hydroxycholesterol
Analysis: Drug repositioning mechanism analysis

OH OH

Compound Structure and Identifier

InChI: InChI=1S/C27H46O2/c1-17(2)6-11-25(29)18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20-,21-,22+,23-,24-,25-,26-,27+/m0/s1 See All
InChI Key: RZPAXNJLEKLXNO-QUOSNDFLSA-N
Smiles: CC(C)CC[C@H](O)[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C See All
Molfile: Download

Related Target

Target ID Name Interaction
T0533 Oxysterols receptor LXR-beta antagonist

Related Fibrosis Property

Reference Record 1

PubMed ID 27746237 Target ID T0533
Uniprot ID Oxysterols receptor LXR-beta Name Oxysterols receptor LXR-beta
Model vitro,human,mice Fibrosis Disease Idiopathic pulmonary fibrosis
Process I
Process II fibroblasts proliferation,fibroblasts migration
Process III
Mechanism Targeting LXR pathway

Related Link

PubChem: 168038
ChEMBL: CHEMBL1243244