AM1241

Basic Information

CAS ID: 444912-48-5
Molecular Formula: C22H22IN3O3
Molecular Weight: 503.3 g/mol
Monoisotopic Mass: 503.0706 g/mol
Class: Small Molecule
Natural Product: No
Other Names: AM-1241
Analysis: Drug repositioning mechanism analysis

N N O I N+ O O-

Compound Structure and Identifier

InChI: InChI=1S/C22H22IN3O3/c1-24-11-5-4-6-16(24)13-25-14-19(17-7-2-3-8-21(17)25)22(27)18-12-15(26(28)29)9-10-20(18)23/h2-3,7-10,12,14,16H,4-6,11,13H2,1H3 See All
InChI Key: ZUHIXXCLLBMBDW-UHFFFAOYSA-N
Smiles: CN1CCCCC1Cn2cc(C(=O)c3cc(ccc3I)[N+](=O)[O-])c4ccccc24 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0135 Cannabinoid receptor 2 agonist

Related Fibrosis Property

Reference Record 1

PubMed ID 27614871 Target ID T0135
Uniprot ID Cannabinoid receptor 2 Name Cannabinoid receptor 2
Model vitro,mice Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting Nrf2-Mediated Inhibition of TGF-β1/Smad3 pathway

Related Link

PubChem: 10141893
ChEMBL: CHEMBL408430