Wnt-C59

Basic Information

CAS ID: 1243243-89-1
Molecular Formula: C25H21N3O
Molecular Weight: 379.5 g/mol
Monoisotopic Mass: 379.1685 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

N O NH N

Compound Structure and Identifier

InChI: InChI=1S/C25H21N3O/c1-18-15-22(12-14-27-18)20-6-4-19(5-7-20)16-25(29)28-24-10-8-21(9-11-24)23-3-2-13-26-17-23/h2-15,17H,16H2,1H3,(H,28,29) See All
InChI Key: KHZOJCQBHJUJFY-UHFFFAOYSA-N
Smiles: Cc1cc(ccn1)c2ccc(CC(=O)Nc3ccc(cc3)c4cccnc4)cc2 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0476 Protein-serine O-palmitoleoyltransferase porcupine inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 27083283 Target ID T0476
Uniprot ID Protein-serine O-palmitoleoyltransferase porcupine Name Protein-serine O-palmitoleoyltransferase porcupine
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I attenue inflammation
Process II fibroblasts proliferation
Process III prevenet collagen deposition
Mechanism Targeting Wnt/β-catenin signaling pathway

Related Link

PubChem: 57519544
ChEMBL: CHEMBL2139947