Protein-serine O-palmitoleoyltransferase porcupine

Basic Information


Uniprot ID: Q9H237
Secondary ID: B2RBN8
Symbol: PORCN
Other Name: MG61,Protein MG61
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Acyltransferase,Transferase


Target Classification


Category I Category II Category III
Intracellular Enzyme Transferase

Related Compound


Target ID Name Interaction
D0152 Wnt-C59 inhibitor

Fibrosis Related Property


Reference Record 1

PubMed ID 27083283 Compound ID D0152
CAS 1243243-89-1 Name Wnt-C59
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I attenue inflammation
Process II fibroblasts proliferation
Process III prevenet collagen deposition
Mechanism Targeting Wnt/β-catenin signaling pathway