Lificiguat

Basic Information

CAS ID: 170632-47-0
Molecular Formula: C19H16N2O2
Molecular Weight: 304.4 g/mol
Monoisotopic Mass: 304.1212 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

OH O N N

Compound Structure and Identifier

InChI: InChI=1S/C19H16N2O2/c22-13-15-10-11-18(23-15)19-16-8-4-5-9-17(16)21(20-19)12-14-6-2-1-3-7-14/h1-11,22H,12-13H2 See All
InChI Key: OQQVFCKUDYMWGV-UHFFFAOYSA-N
Smiles: OCc1oc(cc1)c2nn(Cc3ccccc3)c4ccccc24 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0567 Hypoxia-inducible factor 1-alpha inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 26908870 Target ID T0567
Uniprot ID Hypoxia-inducible factor 1-alpha Name Hypoxia-inducible factor 1-alpha
Model mice Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting NOX4

Related Link

PubChem: 5712
ChEMBL: CHEMBL333985