| CAS ID: | 1262041-49-5 |
| Molecular Formula: | C23H21N7O |
| Molecular Weight: | 411.5 g/mol |
| Monoisotopic Mass: | 411.181 g/mol |
| Class: | Small Molecule |
| Natural Product: | No |
| Other Names: | |
| Analysis: | Drug repositioning mechanism analysis |
| InChI: | InChI=1S/C23H21N7O/c31-23(20-11-19(8-9-24-20)29-12-21(25-13-29)15-4-5-15)27-17-3-1-2-16(10-17)22-28-26-14-30(22)18-6-7-18/h1-3,8-15,18H,4-7H2,(H,27,31) | See All |
| InChI Key: | ZGCMQKWOUIMBEP-UHFFFAOYSA-N | |
| Smiles: | C1CC1C2=CN(C=N2)C3=CC(=NC=C3)C(=O)NC4=CC=CC(=C4)C5=NN=CN5C6CC6 | See All |
| Molfile: | Download |
Reference Record 1
| PubMed ID | 26180085 | Target ID | T0350 |
| Uniprot ID | Mitogen-activated protein kinase kinase kinase 5 | Name | Mitogen-activated protein kinase kinase kinase 5 |
| Model | mice | Fibrosis Disease | Renal fibrosis |
| Process I | attenue inflammation | ||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting ASK1-dependent p38 signaling | ||
| PubChem: | 57504987 |
| ChEMBL: |