Calhex231

Basic Information

CAS ID: 652973-93-8
Molecular Formula: C25H27ClN2O
Molecular Weight: 407 g/mol
Monoisotopic Mass: 406.1812 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

NH NH O Cl

Compound Structure and Identifier

InChI: InChI=1S/C25H27ClN2O/c1-17(21-10-6-8-18-7-2-3-9-22(18)21)27-23-11-4-5-12-24(23)28-25(29)19-13-15-20(26)16-14-19/h2-3,6-10,13-17,23-24,27H,4-5,11-12H2,1H3,(H,28,29)/t17?,23-,24-/m1/s1 See All
InChI Key: YTFUQWWKTIWYEY-LQCDLOPMSA-N
Smiles: CC(N[C@@H]1CCCC[C@H]1NC(=O)c2ccc(Cl)cc2)c3cccc4ccccc34 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0156 Extracellular calcium-sensing receptor inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 26159880 Target ID T0156
Uniprot ID Extracellular calcium-sensing receptor Name Extracellular calcium-sensing receptor
Model rat Fibrosis Disease Cardiac fibrosis
Process I
Process II cells apoptosis
Process III prevenet collagen deposition
Mechanism Targeting CaMKKβ-AMPK-mTOR pathway

Related Link

PubChem: 16043276
ChEMBL: CHEMBL1189741