Extracellular calcium-sensing receptor

Basic Information

Uniprot ID:	P41180
Secondary ID:	Q13912
Symbol:	CASR
Other Name:	GPRC2A,CaR,CaSR,hCasR,Parathyroid cell calcium-sensing receptor 1,PCaR1
Class:	Single Protein
Type:	pro-fibrotic
Molecular Function:	G-protein coupled receptor,Receptor,Transducer

Target Classification

Category I	Category II	Category III
Extracellular	G protein-coupled receptor	Other

Related Compound

Target ID	Name	Interaction
D0195	Calhex231	inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID	26159880	Compound ID	D0195
CAS	652973-93-8	Name	Calhex231
Model	rat	Fibrosis Disease	Cardiac fibrosis
Process I
Process II	cells apoptosis
Process III	prevenet collagen deposition
Mechanism	Targeting CaMKKβ-AMPK-mTOR pathway