Sinefungin

Basic Information

CAS ID: 58944-73-3
Molecular Formula: C15H23N7O5
Molecular Weight: 381.4 g/mol
Monoisotopic Mass: 381.1761 g/mol
Class: Small Molecule
Natural Product: No
Other Names: SINEFUNGIN | COMPOUND 57926
Analysis: Drug repositioning mechanism analysis

NH2 NH2 O HO O OH OH N N NH2 N N

Compound Structure and Identifier

InChI: InChI=1S/C15H23N7O5/c16-6(1-2-7(17)15(25)26)3-8-10(23)11(24)14(27-8)22-5-21-9-12(18)19-4-20-13(9)22/h4-8,10-11,14,23-24H,1-3,16-17H2,(H,25,26)(H2,18,19,20)/t6-,7-,8+,10+,11+,14+/m0/s1 See All
InChI Key: LMXOHSDXUQEUSF-YECHIGJVSA-N
Smiles: N[C@@H](CC[C@H](N)C(=O)O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)ncnc23 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0669 Histone-lysine N-methyltransferase SETD7 inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 26045091 Target ID T0669
Uniprot ID Histone-lysine N-methyltransferase SETD7 Name Histone-lysine N-methyltransferase SETD7
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting H3K4me1

Related Link

PubChem: 65482
ChEMBL: CHEMBL1214186