Histone-lysine N-methyltransferase SETD7

Basic Information


Uniprot ID: Q8WTS6
Secondary ID: B5WWL3
Symbol: SETD7
Other Name: KIAA1717,Histone H3-K4 methyltransferase SETD7,H3-K4-HMTase SETD7,Lysine N-methyltransferase 7,SET domain-containing protein 7,SET79
Class: Epigenetics
Type: pro-fibrotic
Molecular Function: Activator,Chromatin regulator,Methyltransferase,Transferase


Target Classification


Category I Category II Category III
Intracellular Epigenetics Writer

Related Compound


Target ID Name Interaction
D0205 Sinefungin inhibitor

Fibrosis Related Property


Reference Record 1

PubMed ID 26045091 Compound ID D0205
CAS 58944-73-3 Name Sinefungin
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting H3K4me1