Lovastatin

Basic Information


CAS ID: 75330-75-5
Molecular Formula: C24H36O5
Molecular Weight: 404.6 g/mol
Monoisotopic Mass: 404.2563 g/mol
Class: Small Molecule
Natural Product: No
Other Names: ALTOPREV | MK-803 | LOVASTATIN | MEVACOR | MEVINOLIN | MEVINACOR | MEVINACOR 40 | MEVINACOR 10
Analysis: Drug repositioning mechanism analysis

O O OH O O


Compound Structure and Identifier


InChI: InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1 See All
InChI Key: PCZOHLXUXFIOCF-BXMDZJJMSA-N
Smiles: CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 See All
Molfile: Download


Related Target


Target ID Name Interaction
T0495 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor

Related Fibrosis Property


Reference Record 1

PubMed ID 22712078 Target ID
Uniprot ID Name
Model mice Fibrosis Disease Liver fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 25646300 Target ID T0495
Uniprot ID 3-hydroxy-3-methylglutaryl-coenzyme A reductase Name 3-hydroxy-3-methylglutaryl-coenzyme A reductase
Model mice Fibrosis Disease Cardiac fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Related Link


PubChem: 53232
ChEMBL: CHEMBL503